Principal Investigator Chen Chia-Hung
Phone n/a


Department Bioengineering
Address E1-05-27
Engineering Drive 1
Singapore 117575
Lab Website

Integrated Microfluidic Biotechnology


  • M. A. Miller, A. S. Meyer, M. Beste, Z. Lasisi, S. Reddy, K. Jeng, C. H. Chen, J. Han, K. Isaacson, L. G. Griffith, D. A. Lauffenburger, "ADAM-10 regulates cell migration via Jnk/p38 and opposing feedback through dual ligand and receptor shedding in invasive disease" Proceedings of the National Academy of Sciences, 2013, doi: 10.1073/pnas.1222387110
  • C. H. Chen, M. A. Miller, A. Sarkar, M. T. Beste, K. B. Isaacson, D. A. Lauffenburger, L. G. Griffith, and J. Han "Multiplexed Protease Activity Assay for Low-Volume Clinical Samples Using Droplet-Based Microfluidics and Its Application to Endometriosis" Journal of the American Chemical Society, 2013, 135(5), pp1645-1648
  • C. H. Chen, A. Sarkar, Y. Song, M. A. Miller, S. J. Kim, L. G. Griffith, D. A. Lauffenburer and J. Han "Enhancing protease activity assay in droplet-based microfluidics Using a Biomolecule Concentrator" Journal of the American Chemical Society, 2011, 133, pp10368-10371
  • C. H. Chen and E. M. Terentjev "Colloid-monoglyceride composites in hydrophobic solutions" Colloids and Surfaces A, 2011, 384, pp536-542
  • H. C. Shum, A. R. Abate, D. Lee, A. Studart, B. Wang, C. H. Chen, J. Thiele, A. Krummel and D. A. Weitz "Droplet microfluidics for fabrication of non-spherical particles" Macromolecular Rapid Communications, 2010, 31, pp108-118
  • C. H. Chen and E. M. Terentjev "Effects of water on aggregation and stability of monoglycerides in hydrophobic solutions" Langmuir, 2010, 26, pp3095-3105
  • C. H. Chen, A. R. Abate, D. Lee, E. M. Terentjev and D. A. Weitz "Microfluidic assembly of magnetic hydrogel particles with uniformly anisotropic structure" Advanced Materials, 2009, 21, pp3201-3204 (Selected as cover story)
  • C. H. Chen, I. van Damme and E. M. Terentjev "Phase behaviors of monoglyceride C18 in hydrophobic solutions" Soft Matter, 2009, 5, pp432-439
  • C. H. Chen and E. M. Terentjev "Metastability and aging of monoglycerides in hydrophobic solutions" Langmuir, 2009, 25, pp6717-6724
  • C. H. Chen, R. K. Shah, A. R. Abate, and D. A. Weitz "Janus Particles Templated from Double Emulsion Droplets Generated Using Microfluidics" Langmuir, 2009, 25 (8), pp4320-4323
  • A. R. Abate, C. H. Chen, J. Agresti and D. A. Weitz "Beating Poisson encapsulation statistics using close-packed ordering" Lab on a Chip, 2009, 9, pp2628-2631

Invited Papers

  • R. Ramesh, C. X. Ang, J. Y. Ng, C. T. Lim and C. H. Chen " Microfluidic Single Mammalian Cell Lysis in Pico-Litre Droplets" Biosensor and Bioelectronics, 2013 accepted JBSBE-13-1459.
  • R. C. Luo and C. H. Chen "Structured Microgels through Microfluidics Assembly and Their Biomedical Applications" SciRes Soft, 2012, 1, pp1-23.