Spinal Cord Injury & Repair

Available Positions

Open Positions

Inquiries and applications are invited from highly productive, creative and ambitious young scientists for the following positions.

  • Post-Doctoral Fellows
  • Research Scientist
  • Lab Technician/Assistant

Candidates with an MS or PhD degree are welcome to apply. Applicable fields of study are (but not limited to) biomedical engineering, stem cell biology, neurosciences, medicine, and statistics with interests in signal processing, neurophysiology, imaging, cell work, and/or animal care.

Description

The Spinal Cord Injury & Repair Laboratory will be designed and equipped for carrying out in vivo experimental research in rodents. We study a contusive model of spinal cord injury (SCI) using our well-established rodent bodel to mimic clinically relevant injuries in humans. Our laboratory has one universal, long-term aim, which is "treatment of patients with spinal cord injury". However such a multi-disciplinary translational laboratory (bench-to-bed-side) will develop the following inter-connected projects.

  1. Diagnosis and assessments of spinal cord injury through neuroelectrophysiology and quantitative analysis of sensory and motor pathway signals to assess the electrical conductivity and cross-talk at various stages of injury and treatment.
  2. The study of hypothermia treatment for SCI in rodents and the development of a protocol for translational and clinical studies in humans.
  3. Derivation of oligodendrocyte precursor cells, both via induced pluripotent stem cells and via direct conversion from human fibroblasts, for treatment and remyelination of the spinal cord after injury.
  4. Imaging using DT-MRI to monitor anatomical changes in the injured spinal cord architecture at various time points to track the extent of secondary injury and to determine the therapeutic benefits of this approach.
  5. Functional electrical stimulation (FES), rehabilitation and physical therapy to maintain, restore and improve long term functionality of nervous system, musculature and their interaction after SCI and therapy.

Benefits

Researchers will have access to impressive financial and physical resources, including noninvasive human and small animal experimental facilities, laboratory instrumentation, computing and imaging resources, and additional project-specific discretionary funding. SINAPSE will provide excellent work conditions (an environment about 20 collaborative PIs and more than 100 researchers in steady state). The salaries will be internationally competitive and commensurate with experience, and health insurance coverage as well as travel to international conferences will be included.

Contact

For inquiries or to submit your application to the Spinal Cord Injury Laboratory, please contact Dr. Angelo All, MD, MBA at angelo@bme.jhu.edu. Please include a CV with two external references and a letter of accomplishments, motivation and career goals.